Epilepsy: A Queen Square Textbook
01 Jan 2026, Wiley, ISBN Electronic: 9781394340064, ISBN Print: 9781394340033, English, 284 pages
Editors: John S. Duncan & Ley Sander
Comprehensive, cutting-edge guide to adult epilepsy from the renowned Queen Square specialists
Epilepsy: A Queen Square Textbook delivers an authoritative and up-to-date overview of the causes, consequences, diagnosis, and treatment of epilepsy in adults. Written by the distinguished Queen Square Epilepsy group, this complete resource synthesises the relevant evidence and applies the latest knowledge to clinical practice, with points of practical importance highlighted throughout.
This essential reference covers:
Fundamental aspects: The neurosciences of epilepsy and epileptogenesis, neurophysiology, medical imaging, epidemiology, genetics and the spectrum of epileptic seizures and epilepsies
Clinical management: Diagnosis, medical and surgical treatment, neuropsychology, non-pharmacological therapies, status epilepticus, reproduction, epilepsy in older people, sleep, and neurodegeneration
Current challenges: Psychiatric and somatic comorbidities, sudden unexpected death in epilepsy (SUDEP), functional dissociative seizures, driving and the law
Contemporary issues and emerging technologies: Climate change impacts, the role of artificial intelligence in diagnosis and treatment, and future perspectives in epilepsy management
Epilepsy: A Queen Square Textbook is an indispensable resource for healthcare professionals involved in epilepsy care and research, including neurologists, nurses, neuroscientists, and psychologists - from trainees through to established specialists.
Epilepsy Sparks Insights podcast episodes - with the authors
When Epilepsy Meds Fail - Where Neuromodulation Fits - Prof. John Duncan
Epilepsy Caused By Worms - Prof. Ley Sander
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John Duncan is a Consultant Neurologist specialising in epilepsy, practicing at the National Hospital for Neurology and Neurosurgery, Queen Square, London and at Chalfont Centre for Epilepsy, His personal research focus is neuroimaging applied to epilepsy surgery.
He was appointed Professor of Neurology at the UCL Institute of Neurology in 1998. From 2012 to 2018 he was Clinical Director of the National Hospital for Neurology and Neurosurgery. He is NIHR Senior Investigator and Governor of UCL Hospitals. He is Honorary Professor of Neurology, Fudan University, Shanghai, China. Visiting Professor, Faculty of Life Sciences & Medicine, Kings College London.
In 2004, John received the annual Clinical Research recognition award of the American Epilepsy Society. He is past-President and past treasurer of the UK chapter of ILAE. In 2005 he was elected Ambassador for Epilepsy and to be a Fellow of the Academy of Medical Sciences. In 2025 he was elected to the European Academy.
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Ley qualified in Medicine in 1981 (Medico, Universidade Federal do Parana, Curitiba, Brazil), then he completed medical and specialist training in Neurology in London at St Thomas Hospital and the National Hospital for Neurology and Neurosurgery. He is registered with the General Medical Council (GMC No.3425310) and in the Neurology specialist register. He obtained a PhD at the University of London in 1994. He is an elected Fellow of the Royal College of Physicians, the European Academy of Neurology, and the Academy of Medical Sciences. He is also a member of the Academia Europaea.
Ley is Professor of Neurology and Clinical Epilepsy and the former head of the Department of Clinical and Experimental Epilepsy at UCL Queen Square Institute of Neurology. Apart from his UCL duties, he is an honorary Consultant Neurologist specialising in Epilepsy at the National Hospital for Neurology and Neurosurgery (Queen Square) and the Chalfont Centre for Epilepsy in Buckinghamshire. Since 2019, Ley has been a Professor of Neurology at Sichuan University in China. Until 2018, he directed the WHO Collaborating Centre for Research and Training in Neurosciences in London and the WHO Collaborating Centre for Research, Training and Treatment of Epilepsy in Heemstede, Netherlands. Between 2007 and 2024, Ley was the R&D Director of Stichting Epilepsie Instellingen Nederland (SEIN), in Heemstede, The Netherlands. He was also the Medical Director of the Chalfont Centre for Epilepsy between 2012 and 2025.Global health is one of Ley’s interests and is a key aspect of his work. He has been involved in setting up epilepsy services over the years and conducted epilepsy research in China, Brazil, Ecuador, Georgia, India, Bulgaria, Kenya, Senegal, Cameroon, Nigeria, Tanzania and Ghana.